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Surgery versus Conservative OsteOarthritis of Thumb Trial
The SCOOTT Trial
SCOOTT is a multi-centre, superiority and non-inferiority three-arm RCT which aims to answer two important questions regarding treatment of base of thumb osteoarthritis (BTOA):
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Is surgery [Trapeziectomy or Carpometacarpal Joint Replacement (CMCJR)] superior to enhanced non-surgical management?
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Is CMCJR non-inferior to trapeziectomy?
Trial Updates:
Number of Participants Recruited:
158
Number of Sites Open to Recruitment:
14
December Recruitment:
Target - 166 Participants
Recruited - 156 Participants
100%
0%
156
Open Sites
South Tees Hospitals NHS Foundation Trust
University Hospitals of Derby and Burton NHS Foundation Trust
Liverpool University Hospitals NHS Foundation Trust
East Suffolk and North Essex NHS Foundation Trust
The Rotherham NHS Foundation Trust
Wrightington, Wigan and Leigh Teaching Hospitals NHS Foundation Trust
University Hospital Southampton NHS Foundation Trust
East Kent Hospitals University NHS Foundation Trust
Oxford University Hospitals NHS Foundation Trust
Maidstone and Tunbridge Wells NHS Trust
Chelsea and Westminster Hospital NHS Foundation Trust
County Durham and Darlington NHS Foundation Trust
Royal Surrey NHS Foundation Trust
The Royal Orthopaedic Hospital NHS Foundation Trust
Last Updated: January 2026
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